Summary of clinical results

Evaluation of the tolerance and efficacy of EPITHELIALE ULTRA REPAIR (A.H ULTRA) soothing repair cream in adult patients with skin irritations on the face and/or body.
Objective
To evaluate the tolerability and efficacy of EPITHELIALE ULTRA REPAIR (A.H ULTRA) soothing repair cream in adult patients with skin irritations.
Methodology
45 adults aged 18 to 70 years were included:
- Post-shave: 11
- Solar erythema (mild intensity): 12
- Insect bites: 12
- Excoriated acne: 10
Design
Apply once or twice a day to irritated skin on the face and/or body for 22 days.

Evaluation criteria
Evaluation of skin tolerance.
Evaluation of reparative efficacy, soothing efficacy and sensations of discomfort.
Results
Skin tolerance was judged to be very good by the investigator.
With an improvement in clinical signs from the 1st application
Clinically significant 17% reduction in erythema
Clinically significant 67% reduction in dryness [p=0.011].
and improvement in functional signs:
56% clinically significant reduction in itching
56% clinically significant reduction in burning sensation
Clinically significant 50% reduction in tingling sensation
Efficacy
Evaluation of cutaneous discomfort (cutaneous pain)
86% reduction in skin pain at D3 (versus baseline).

Evaluation of soothing efficacy
Soothing effect felt from 1st application, increasing significantly up to day 22.

Assessment of reparative efficacy
Very good reparative efficacy observed after 2 days for 48% of patients and for 89% of patients at D22.

Conclusion
EPITHELIALE ULTRA REPAIR (A.H ULTRA) repair cream has a very good skin tolerance and proven efficacy on discomfort, soothing and skin repair.
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