Summary of clinical results

Tolerance and efficacy of CICALFATE+ cleansing gel alone
Tolerance and efficacy of CICALFATE+ cleansing gel alone in infants, children, teenagers and adults with skin irritations on the face or body, under dermatological, pediatric and gynecological control.
Population
89 subjects aged 4 months to 85 years with skin irritations on the face, body or scalp:
- Vulvar irritations (n=16)
- Post-tattoo (n=12)
- diaper rash (n=11)
- Post-glycolic acid peel (n=6)
- Post-laser KTP (n=5)
- Other irritations (n=39)
Application of CICALFATE+ purifying cleansing gel
- 1 to 2 applications per day on skin irritations (face, body or scalp) for 3 weeks
Evaluation criteria
- Evaluation of clinical and functional signs associated with skin irritation (score from 0=absent to 4=severe)
- Auto-evaluation of sensations of discomfort (score from 0 to 10)
- Skin and gynecological tolerance
Results
Statistically significant reduction in all physical and functional signs associated with skin irritation immediately after application (p<0,05, versus T0)
Significantly soothed discomfort immediately after first application: -20% (p<0.05, versus T0)

Changes in intensity of discomfort sensations over 3 weeks
*p= significant (p<0.05, versus T0 ; ** p= highly significant (p<0.001, versus T0)
Good skin tolerance and excellent gynecological tolerance
Conclusion
CICALFATE+ purifying cleansing gel 1 to 2 times a day:
- improves signs of irritation from the first application
- alleviates sensations of discomfort from the first application
Good skin tolerance and excellent gynaecological tolerance
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