Summary of clinical results

AVENE
Cicalfate SPF50+ PACKSHOT

Tolerance and efficacy of CICALFATE+ SPF50+ Multi-protective skin repair cream​

Tolerance and efficacy of CICALFATE+ multi-protective repair cream SPF50+ as monotherapy on infants, children and adults with irritated skin, under dermatological control.

Population

87 subjects aged 3 months to 68 years with skin irritations:

  • Post-laser KTP irritations (n=10)
  • Post-glycolic acid 10% peel irritations (n=10)
  • Post-cryotherapy irritations (n=10)
  • Post-pulsed light irritations (n=10)
  • Post-tattooing (n=10)
  • Various irritations (n=37)

 

Application of CICALFATE+ protective repair cream

2 applications per day to irritated areas (face, body) for 3 weeks

 

Evaluation criteria

  • Clinical scoring of reparative efficacy (Score from 0=ineffective to 3=very effective)
  • Clinical scoring of improvement in irritation (Score from 0=ineffective to 3=very effective)
  • Clinical scoring of antimarks (Score from 0=ineffective to 3=very effective)
  • Self-assessment of sensations of discomfort (score from 0 to 10)
  • Measurement of redness
  • Skin tolerance

Results

  • Repair effectiveness demonstrated as early as D2 (48h): product effective to very effective for 82% of subjects, observed by dermatologist
Results 3 weeks cicalfate+
Evolution of restorative efficacy (effective to very effective) over 3 weeks
  • Red marks significantly reduced: -34% at 3 weeks (p<0.001, versus T0)
Cicalfate+ results week 3
Change in red mark intensity over 3 weeks ** p= Statistically Highly Significant (p<0.001, versus T0)
  • Very good skin tolerance 
     

Conclusion

CICALFATE + SPF50+ Multi-protective skin repair cream​ SPF50+ applied twice daily:

  • Demonstrated reparative efficacy as early as 2 days
  • Demonstrated efficacy on red marks as early as 2 days
  • Very good skin tolerance