Summary of clinical results

AVENE
Soin hydratant réparateur.

Tolerance and efficacy in monotherapy of CICALFATE+ hydrating skin repairing emulsion​

Tolerance and efficacy of CICALFATE+ repairing moisturizer as a monotherapy treatment on post-act or post-tattoo adults, under dermatological control.

Population

62 subjects aged 18 to 65 with post-act or post-tattoo skin irritations:

  • Tattooing (n=19)
  • Pulsed light (n=11)
  • ND Yag laser. (n=11)
  • Peeling (n=9)
  • Laser KTP (n=6)
  • Microneedling (n=6)

Application of CICALFATE+ hydrating skin repairing emulsion​

  • 2 applications per day on irritated areas (face or body) for 3 weeks

Evaluation criteria

  • Evaluation of clinical and functional signs associated with skin irritation (score from 0=absent to 4=severe)
  • Clinical rating of reparative efficacy (Ineffective to very effective)
  • Clinical rating of antimarks (Ineffective to very effective) 
  • Self-assessment of burning sensations (score from 0 to 10)
  • Skin tolerance

Results

  • Statistically significant reduction in all physical and functional signs associated with skin irritation immediately after application (p<0,05, versus T0)

  • Repairing efficacy rated good to very good by investigators for 90% of subjects from 2 days of application

Image 1

Investigator rating of reparative efficacy over 3 weeks

 

  • Antimark rated good to very good by investigators for 98% of subjects after 2 days of application

  • Significantly soothed burning sensations from the first application: -60% (p<0.001, versus T0)
  • Very good skin tolerance

Conclusion

CICALFATE+ hydrating skin repairing emulsion​ applied twice-daily post-act or post-tattoo :

  • has demonstrated repairing and anti-marking efficacy as early as 2 days of application
  • alleviates burning sensations as early as the first application

Very good skin tolerance