Population

44 subjects aged 33 to 65 with erythematotelangiectatic rosacea:

• Mild to moderate erythema (localized or diffuse)

• Mild to moderate telangiectasia

100% of subjects with sensitive skin

Application of ROSAMED Chronic redness concentrate

2 applications per day on face, neck and décolleté for 4 weeks

Assessment criteria

• Auto-assessment of flush severity (GFSS = Global Flushing Severity Score) and flush frequency (score from 0 to 10)
• Auto-assessment of subjective signs associated with erythematotelangiectatic rosacea (tingling sensations, burning, heat, discomfort)
• Skin and eye tolerance

Evolution of flush frequency over 4 weeks

** p= statistically Highly Significant (p<0,001, versus D1)

Significant improvement in subjective signs associated with erythematotelangiectatic rosacea at 1 month:

• -71% intensity of tingling sensations (p<0.001, versus D1)
• -58,7% intensity of pulling sensations (p<0.001, versus J1)
• -56.8% intensity of burning sensations (p<0.05, versus D1)
• -17,7% intensity of discomfort sensations (p<0.001, versus D1)

Good skin tolerance and excellent ocular tolerance

Conclusion

ROSAMED Chronic redness concentrate applied twice daily :

• has demonstrated efficacy on the intensity and frequency of flushing as early as 2 weeks
• reduces associated signs of discomfort

Good cutaneous tolerance and excellent ocular tolerance