Summary of clinical results
AVENE

Tolerance and efficacy study of HYALURON ACTIV Tensor Serum PROCEDURE
Tolerance and efficacy study of HYALURON ACTIV PROCEDURE Tensor Serum on targets
Population
40 subjects aged 52 to 65 with moderate to severe wrinkles.
Application
2 applications per day for 2 weeks
Evaluation criteria
- Improvement of (static) wrinkles by fringe projection
- Improvement in facial relaxation by measurement of expression lines using fringe projection (60 seconds after a smiling facial expression then relaxation)
- Skin brightness/radiance by spectrocolorimeter and clinical rating (scale from 0 to 10)
- Firmness / elasticity by cutometer
- Refined skin by clinical rating (scale from 0 to 10)
Results
After 14 days of serum use:
- 18.6%** improvement in skin texture (N=40)
- 22.3%** improvement in complexion radiance(N=40)
- 8.6%** reduction in crow's feet expression lines (N=39)
- 11.4%* reduction in forehead wrinkles (N=15)
- Nasolabial wrinkles reduced by -8.6%** (N=15)
*p<0.05 vs T0 **p<0.001 vs T0

Conclusion
HYALURON ACTIV PROCEDURE Lifting Serum has been clinically proven effective on wrinkles, radiance and luminosity of the complexion after 14 days of use.
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