Summary of clinical results
Dexeryl emollient cream, an effective treatment for skin xerosis in sub-Saharan African patients
Objective
To evaluate the efficacy of an emollient cream (Dexeryl) on skin xerosis in sub-Saharan African patients.
Study
Prospective multicenter longitudinal study. 7 countries: Benin, Burkina Faso, Cameroon, Ivory Coast, Gabon, Mali and Senegal.
Population
185 patients from sub-Saharan countries (56 children and 129 adults).
Dosage
2 applications daily.
Duration
8 weeks.
Primary endpoint
Evaluate the evolution of xerosis (SRRC score) from baseline to week 8 (pre- and post-Dexeryl treatment).
Secondary endpoints
Change in SRRC score at week 4
Change in pruritus score at baseline, week 4 and week 8 (PO-SCORAD score)
Clinical improvement at week 4 and week 8 (CGI-A and PGIC scores)
Assessment of quality of life at week 8 (DLQI score)
Compliance and tolerance
Subjects' and practitioners' opinions of treatment
Tolerance
Dexeryl emollient cream is safe and well accepted.
Conclusion
+ 80% significant reduction in cutaneous dryness in children and adults.
Regular application of Dexeryl emollient cream twice a day to the body significantly reduces skin dryness by 83.9% in children and 80.4% in adults within 2 months¹. It also reduces itching in children by 80.6% after 2 months of treatment1. 90% of patients and doctors are satisfied with Dexeryl emollient cream¹.
Publication
1 - Boralevi et al. Regression of cutaneous xerosis with emollient treatment in sub-Saharan African patients. Int. J. Dermatol. 2017
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