Publication Summary

AVENE

Effects of the Staphylococcus aureus and Staphylococcus epidermidis Secretomes Isolated from the Skin Microbiota of Atopic Children on CD4+ T Cell Activation

Emeline Laborel-Préneron, Pascale Bianchi, Franck Boralevi, Philippe Lehours, Frédérique Fraysse, Fanny Morice-Picard, Motoyuki Sugai, Yusuke Sato'o, Cédric Badiou, Gérard Lina, Anne-Marie Schmitt, Daniel Redoulès, Christiane Casas, Christian Davrinche
Plos ONE
2015

Atopic dermatitis is a pathology associated with a dysfunction of the skin barrier, excessive colonization of the Staphylococcus aureus bacteria and anomalies affecting the immune system. 
A study was published in 2015 in the Plos One journal (Impact Factor: 2.766) and showed the role played by commensal flora in the regulation of our immune responses. 
S. epidermidis, the bacteria most representative of commensal flora, has an anti-inflammatory effect which counters that of inflammatory S. aureus, meaning that S. epidermidis has an immunomodulatory effect.

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