False culprit

  • Adnexal diseases
Dr. Emmanuelle Bourrat
Saint-Louis Hospital
  • The clinical case
  • Now it's your turn!
  • Co-prescription and advice

Clinical case presentation

A 9-year-old girl was hospitalized in a child psychiatry unit for a first severe depressive episode with catatonia associated with hallucinatory symptoms. Two weeks after initiation of treatment with an antipsychotic whose therapeutic activity involves binding to dopaminergic and serotonergic receptors, the dermatologists were called in for diffuse, incomplete but sudden and spectacular alopecia.

The child was very oppositional, unresponsive to questions and did not allow her very thinning hair to be closely examined (photo 1). The hair did not appear dysplastic, the scalp was not inflamed and the eyelashes, eyebrows, body hair and nails were normal. Nutritional status was satisfactory and biological tests showed no iron deficiency or thyroid dysfunction.

Your turn

What is your diagnosis?

Select 1 answer(s) from the following choices:

Selected diagnosis

At the end of the consultation, while the dermatologist was writing up the clinical notes, the patient reached into her hair (photo 2) and pulled out a tuft, which joined a “ball” of hair (photo 3) previously removed in the same way, thus confirming trichotillomania.

Trichotillomania, defined as the compulsive habit of pulling out one’s own hair, is seven times more frequent in children than in adults. While its psychopathological origin is often absent in very young children, in whom it resembles a sleep ritual, it can have a more negative significance in older children and, as in our case, can occur in a context of anxious agitation or self-harm.

Diagnosis is sometimes difficult, as broken hairs, sometimes very short and of varying lengths, are not always easy to identify clinically. Dermoscopic examination can then provide evidence supporting this diagnosis: very short broken hairs at different lengths and microhemorrhages at the follicular openings.

Explanation of wrong answers

  • Drug-induced alopecia: Psychiatrists and parents are concerned about the iatrogenic nature of this alopecia and the need to discontinue and replace the psychotropic drug with another medication. Some psychotropic drugs and tricyclic antidepressants are responsible for abnormal hair loss, but this side effect has been described only once in the literature with the antipsychotic taken by the young patient, and its frequency is estimated at less than 0.01%.
     
  • Diffuse alopecia areata: This is a rare form of alopecia (1%) that does not begin with patches but immediately involves the entire scalp, although not all hair follicles.
     
  • Telogen effluvium: This is the most frequent cause of diffuse alopecia and it has a good prognosis, provided the cause is identified and treated. Our patient had no weight loss, iron deficiency or thyroid disorder.

Treatment

The treatment of trichotillomania constitutes part of the overall management of the underlying psychiatric or psychological disorder.

Message from the expert

Trichotillomania is not an uncommon cause of alopecia in children. It should be systematically considered and confirmed if necessary by dermoscopic examination.

References :

Chandran NS, Novak J, Iorizzo M, Grimalt R, Oranje AP. Trichotillomania in Children.
Skin Appendage Disord. 2015 Mar;1(1):18-24

Find your clinical cases

BlisterRed
Mucosal pathology
Blisters on the vermilion border of the lip
Dr. Emmanuelle Bourrat
nodules muqueux 3
Paediatric dermatology
Mucosal pathology
Mucous nodules and cutaneous papules
Dr. Emmanuelle Bourrat
New
1mosaicisme
Paediatric dermatology
Pigmentation disorder
Don’t confuse rowan leaves with begonia leaves
Dr. Emmanuelle Bourrat