Summary of clinical results

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Tolerance and effectiveness of CLEANANCE HYDRA Soothing Cream

Tolerance and efficacy of CLEANANCE HYDRA Soothing Cream in teenagers and adults undergoing systemic or topical anti-acne treatments, under dermatological control.

Population

42 subjects aged 13 to 27 undergoing systemic or topical anti-acne treatments:

  • 47.7% oral isotretinoin

  • 18,2% benzoyl peroxide

  • 18.2% topical retinoid

  • 15.9% adapalene + benzoyl peroxide

Application of CLEANANCE HYDRA Soothing Cream

2 applications per day on face and back for 4 weeks

Evaluation criteria

  • Evaluation of physical and functional signs of skin irritation (clinical scores from 0 to 4)
  • Subject satisfaction
  • Skin tolerance

Results

  • Significant reduction in xerosis from the first application: -76.8% (p<0.05, versus D1)
image 1

Change in xerosis (clinical score) over 4 weeks

* p= Statistically Significant (p<0,05, versus D1)

 

  • Significant reduction in erythema from first application: - 21.6% (p<0.05, versus D1)
Image 2

Evolution of erythema (clinical score) over 4 weeks

* p= Statistically Significant (p<0.05, versus D1)

 

  • Significant reduction in pruritus and tightness from the first application: - 76.5% and -75% respectively (p<0.05, versus D1)

  • 86% of subjects said that CLEANANCE HYDRA Soothing Cream helped them cope with treatment-induced xerosis and irritation

  • Excellent skin tolerance

Conclusion

CLEANANCE HYDRA Soothing Cream applied twice daily reduces skin irritations related to systemic or topical anti-acne treatments from the very first application

Excellent skin tolerance

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