Summary of clinical results

AVENE
Gel Nettoyant

Tolerance and efficacy in monotherapy of CLEANANCE Cleansing gel

Tolerance and efficacy of CLEANANCE gel cleanser as monotherapy in adolescents and adults with oily, acne-prone skin, under dermatological and ophthalmological control.

Population

52 subjects aged 12 to 37 with oily skin and mild to moderate acne with a total of 10 to 30 acne lesions (at least 5 non-inflammatory and at least 5 inflammatory lesions) on the face

Application of CLEANANCE cleansing gel

2 applications per day on face, upper back and chest for 4 weeks

Evaluation criteria

  • Lion count
  • Skin gloss measurement (clinical score from 0 = non-shiny skin to 9 = very shiny)
  • Evaluation of sebum levels (Sebum Lipid Index)
  • Skin and eye tolerance

Results

  • Highly significant decrease in the number of acne lesions as early as D15: -24% of retention lesions and -47% of inflammatory lesions (p<0.001, versus D1)
Image 1

Change in number of acne lesions (non-inflammatory, inflammatory) over 4 weeks

** p= statistically Highly Significant (p<0,001, versus D1)

 

  • Highly significant reduction in skin shine immediately after application: - 16% (p<0.001, versus D1)
Image 2

Changes in skin gloss (clinical rating) over 4 weeks

** p= statistically Highly Significant (p<0,001, versus D1)

 

  • Highly significant decrease in lipid levels from D15 measured by sebumetry: -27% (p<0.001, versus D1)
Image 3

Evolution of lipid index (sebum meter) over 4 weeks

** p= statistically Highly Significant (p<0,001, versus D1)

 

  • Excellent skin tolerance, including in subjects with sensitive skin

  • Very good ocular tolerance, including in subjects wearing contact lenses or with sensitive eyes

Conclusion

CLEANANCE cleansing gel  used twice daily demonstrated efficacy on oily acne-prone skin as early as 2 weeks, by significantly reducing the number of acne lesions and the quantity of sebum

Excellent skin tolerance and very good ocular tolerance

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