Summary of clinical results

AVENE
Comedome Soin asséchant localisé

Tolerance and efficacy in monotherapy of CLEANANCE COMEDOMED localized drying emulsion​ - Comparative study in hemifacial application

Tolerance and efficacy of CLEANANCE COMEDOMED localized drying care as monotherapy in adults with inflammatory facial acne, under dermatological control

Comparative hemi-face study

Population

16 subjects aged 18 to 31 with inflammatory facial acne (at least 2 recent and comparable inflammatory lesions on each hemiface)

Application of CLEANANCE COMEDOMED localized drying emulsion

  • 3 applications per day on inflammatory lesions on half the face for 2 weeks

Evaluation criteria

  • Clinical grading of the severity of inflammatory lesions (Score from -1= worsening to 4= very good improvement)
  • Skin tolerance

Results

  • Improvement in the severity of inflammatory lesions as early as D2, compared with the untreated hemiface: 37.5% of subjects improved versus 0% for the untreated hemiface
image 1

Evolution of inflammatory lesion severity (clinical score) over 2 weeks, versus untreated hemiface

 

  • Good skin tolerance

Conclusion

CLEANANCE COMEDOMED localized drying emulsion applied three times a day demonstrated an improvement in the severity of inflammatory lesions as early as 1 day of application, compared to an untreated control

Good skin tolerance and excellent ocular tolerance

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