Summary of clinical results

AVENE
Comedome Soin asséchant localisé

Tolerance and efficacy in monotherapy of CLEANANCE COMEDOMED localized drying emulsion

Tolerance and efficacy in monotherapy of CLEANANCE COMEDOMED localized drying emulsion in adolescents and adults with inflammatory facial acne, under dermatological and ophthalmological control.

Population

41 subjects aged 12 to 28 with inflammatory facial acne (5 to 10 inflammatory lesions)

Application of CLEANANCE COMEDOMED localized drying emulsion

3 applications per day on inflammatory lesions on the face for 4 weeks

Evaluation criteria

  • Volume of inflammatory lesions (clinical scoring)
  • Clinical scoring of erythema of inflammatory lesions (Score from 0 to 4)
  • Cutaneous and ocular tolerance

Results

  • Significant decrease in the volume of inflammatory acne lesions as early as D2: -11.5% (p<0.05, versus D1T0)
image 1

Change in acne lesion volume (clinical score) over 4 weeks

* p= Statistically Significant (p<0,05, versus J1T0)

 

  • Significant reduction in erythema of inflammatory acne lesions from D2: - 6.2% (p<0.05, versus D1T0)
Image 2

Evolution of erythema (clinical score) over 4 weeks

* p= Statistically Significant (p<0,05, versus D1)

 

  • Good skin tolerance and excellent ocular tolerance

Conclusion

CLEANANCE COMEDOMED localized drying emulsion applied three times a day demonstrated efficacy on the volume and redness of inflammatory lesions as early as 1 day of application

Good skin tolerance and excellent ocular tolerance

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