Summary of clinical results

DUCRAY
Kelual DS - Shampoing intensive 1

Tolerance and efficacy of KELUAL DS Shampoo Intensive

Tolerance and efficacy of KELUAL DS Shampoo Intensive in subjects with seborrheic dermatitis and associated itching, under dermatological control.

Population

33 adult subjects with seborrheic dermatitis of the scalp and associated itching ≥ 5

 

Application of KELUAL DS Shampoo Intensive

  • Attack phase: 3 shampoos per week for 2 weeks
  • Persistence phase: 72h without shampooing

 

Evaluation criteria

  • Clinical examination of scalp
  • Investigator's score: severity of flaking, erythema
  • Scoring by subject: average itching, burning sensation, impact on quality of life
  • Measurement of transepidermal water loss
  • Measurement of skin pH 

 

Results

  • Anti-recurrence effect 72 hours after stopping use of KELUAL DS Intensive shampoo
  • Up to -82.7% itching sensation, i.e. 4x less scratching after 2 weeks
  • Up to -86.6% severity of flaking after 2 weeks
  • +78.5% improvement in quality of life score after 2 weeks
  • Up to -100% burning sensation after 2 weeks
  • Up to -87.7% erythema after 2 weeks
  • Respect for the scalp and physiological pH of the skin

 

Conclusion

  • Effective on flaking, itching, burning sensation and erythema from 1st application
  • Anti-recurrence efficacy 72 hours after stopping use of KELUAL DS Intensive shampoo
  • Improved quality of life for patients
  • Preservation of the scalp's barrier function and physiological pH level

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