Summary of clinical results

DUCRAY
Keracnyl serum

Tolerance and efficacy of KERACNYL serum in monotherapy

Tolerance and efficacy of KERACNYL serum in monotherapy in adult women with mild to moderate acne, crow's feet wrinkles and fine lines, under dermatological control

Population

60 adult women aged 20-50: 

  • 30 subjects with mild to moderate facial acne, with at least one Post-Inflammatory Erythema (PIE) and/or Post-Inflammatory Hyperpigmentation (PIH)
  • 30 subjects with wrinkles and fine lines in the crow's feet area (score ≥ 2 and < 4 according to the Bazin photographic atlas)

 

Application of KERACNYL serum

Application twice a day (morning/evening) to the entire face for 8 weeks

 

Evaluation criteria

  • Clinical scoring of efficacy on acne lesions: Lucky Method acne lesion count
  • Evaluation of efficacy on residual marks due to inflammation and hyperpigmentation (PIE and PIH)
  • Evaluation of anti-aging efficacy by analysis of the crow's feet prints (maximum depth of wrinkles / fine lines)
  • Skin tolerance
     

Results

  • From 7 days, significant decrease in the number of total inflammatory lesions, which continues to reach –62% after 8 weeks
EN-Keraclyn Serum · Nombre de lésions inflammatoires.png
  • At 1 month, significant decrease in the surface area of post-inflammatory hyperpigmentation lesions of -42% (p<0.05)
EN-Keracnyl Serum - Evolution lésions.png
  • A 1 month, significant decrease in the maximum depth of wrinkles of –20% (p<0.05)
  • Good skin tolerance

 

Conclusion

  • Efficacy on Acne in adult women from 7 days
  • Anti-wrinkle and anti-fine line action
  • Good tolerance 

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