Summary of clinical results
DUCRAY

Tolerance and efficacy of DEXYANE ultra-rich cleansing gel
Tolerance and efficacy of DEXYANE ultra-rich cleansing gel in patients with mild to moderate atopic eczema, under dermatological and pediatric control
Population
46 subjects (17 adults, 16 children, 13 infants) with mild to moderate atopic eczema (SCORAD between 15 and 25)
Application of DEXYANE ultra-rich cleansing gel
Application once a day for 4 weeks, to the face, body and scalp of infants
Usual emollient authorized
Evaluation criteria
- Evolution of the severity of atopic eczema via the SCORAD questionnaire (Scoring atopic dermatitis)
- Scoring of the intensity of xerosis (4-point scale; 0 = absent to 4 very severe) and pruritus (VAS)
- Skin tolerance under dermatological and pediatric control
- Cosmetic acceptability
Results
- Significant decrease in SCORAD of xerosis of –46% after 4 weeks of application (p<0.05)
- Significant decrease in pruritus intensity of -56% after 3 weeks of application (p<0.05)
- Significant decrease in the intensity of xerosis of –57% after 4 weeks of application (p<0.05)
- Soothed skin immediately after application for 91% of patients
- Good skin tolerance
Conclusion
- Reduction of xerosis and pruritus associated with atopic eczema
- Good skin tolerance
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