Summary of clinical results

DUCRAY
Dexyane Crème

Tolerance and efficacy of DEXYANE anti-scratching emollient cream

Tolerance and efficacy of DEXYANE anti-scratching emollient cream in patients with mild to moderate atopic eczema, under dermatological and pediatric control

Population

555 subjects (22 adults, 17 children, 16 infants) with mild to moderate atopic eczema (SCORAD between 10 and 25)

 

Application of DEXYANE anti-scratching emollient

Application once a day for 3 weeks, to the face and body
Usual cleansing product

 

Evaluation criteria

  • Evolution of the severity of atopic eczema via the SCORAD questionnaire (Scoring atopic dermatitis)
  • Scoring of the intensity of xerosis (4-point scale; 0 = absent to 4 very severe) and pruritus (VAS)
  • Evaluation of the intensity of pruritus and its impact on quality of life (patient questionnaire)
  • Skin tolerance under dermatological and pediatric control 
     

Results

  • Significant decrease in SCORAD of –58% after 1 week of application and –69% after 3 weeks (p<0.05)
EN-Dexyane Crème · SCORAD.png
  • Significant decrease in pruritus intensity of -92% after 3 weeks of application
EN-Dexyane Crème · Prurit.png
  • Significant decrease in the intensity of xerosis of -43% after 3 weeks of application.
  • Decrease in the intensity of pruritus and its impact on the quality of daily life perceived by the subjects after 3 weeks of application
  • Very good skin tolerance
     

Conclusion

  • Soothing effect on the clinical signs of atopic eczema
  • Very good skin tolerance

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