Population

43 subjects (11 adults, 16 children, 16 infants) with mild to moderate atopic eczema (SCORAD between 10 and 25 at inclusion)

Application of DEXYANE protective cleansing oil

Application once or twice a day (based on cleansing habits) for 3 weeks, to the face and body 
Usual emollient authorized

Evaluation criteria

• Evolution of the severity of atopic eczema via the SCORAD questionnaire (Scoring atopic dermatitis)
• Scoring of the intensity of xerosis (4-point scale; 0 = absent to 4 very severe) and pruritus (VAS)
• Skin tolerance evaluated under dermatological and pediatric control 
• Cosmetic acceptability
   

Results

• Significant decrease in SCORAD of –29% after 1 week of application and –73% after 3 weeks (p<0.05)
• Significant decrease in pruritus intensity of -91% after 3 weeks of application (p<0.05)
• Significant decrease in xerosis intensity of –62% after 3 weeks of application (p<0.05)
• Immediately soothed and comfortable skin for 100% of patients
• Excellent skin tolerance
   

Conclusion

• Reduction of xerosis and pruritus associated with atopic eczema
• Excellent skin tolerance